Highly diastereoselective approach to methylenecyclopropanes via boron-homologation/allylboration sequences.
نویسندگان
چکیده
A simple and efficient diastereoselective synthesis of methylenecyclopropanes is described, in which boron-homologation and allylboration are merged into a one-pot process, starting from in situ generated cyclopropenyllithium species. This unprecedented methodology opens a new route to strained alkylidenecycloalkanes containing a quaternary stereocenter, in high yields and excellent diastereomeric ratios.
منابع مشابه
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عنوان ژورنال:
- Chemical communications
دوره 52 12 شماره
صفحات -
تاریخ انتشار 2016